This study investigates Parkinson's disease, focusing on identifying a biomarker that can indicate the presence of the disease. Participants will be involved in the study for a total duration of 24 months, with visits spaced 12 months apart.
Study procedures include imaging scans such as Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic Resonance Imaging (MRI). PET and SPECT scans use small amounts of radiation and tracers to study brain chemical changes, while the MRI uses magnetic fields to create images of brain structure and function. Participants may also have the option for a lumbar puncture to collect spinal fluid.
- Who can participate: Participants aged 25 and older who can travel to the research sites and comply with study procedures may be eligible. Women must be non-pregnant and use effective contraception, and men must agree to use condoms and effective contraception.
- Study details: Participants will undergo imaging scans and may have an optional lumbar puncture. A placebo is not used in this study.
- Study timelines and visits: The study will last 24 months. The study requires 8 visits.
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