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Transcranial Direct Current Stimulation of the Primary Motor Cortex to Treat Levodopa-induced Dyskinesias

Transcranial Direct Current Stimulation of the Primary Motor Cortex to Treat Levodopa-induced Dyskinesias

Recruiting
30-80 years
All
Phase N/A

Overview

The main objective of the study is to evaluate the efficacy of 10 sessions of transcranial direct current stimulation of the primary motor cortex to reduce levodopa-induced dyskinesia

Eligibility

Inclusion Criteria:

  • patients with diagnosis of idiopathic Parkinson's disease according to Movement Disorder Society (MDS) criteria and levodopa-induced dyskinesia;
  • age between 30 and 80 years;
  • ongoing therapy with levodopa;
  • fulfillment of requirements for the application of transcranial magnetic stimulation (TMS), assessed by completion of the TMS screening questionnaire.

Exclusion Criteria:

  • patients unable to give informed consent;
  • cognitive impairment (MMSE ≤ 24);
  • history of epilepsy;
  • pregnant women.

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Study details
    Parkinson Disease

NCT05752240

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

9 March 2024

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