Study Overview: This study is looking at children and young adults aged 1 to 25 years with a blood cancer called B-ALL, who have been treated with a special therapy called Chimeric Antigen Receptor T-cell (CART) therapy. This therapy helps the immune system fight cancer. Researchers want to see if regular blood and bone marrow tests can help monitor and prevent cancer from coming back.
Key Medical Terms:
- B-ALL: A type of cancer affecting blood and bone marrow.
- CART therapy: A treatment that uses special cells to target and destroy cancer cells.
- HCT: Hematopoietic Cell Transplant, a procedure to replace damaged blood-forming cells.
- Participants will have clinic visits every 2 weeks for 2 years, starting 42 days after CART.
- Tests include blood draws and bone marrow exams to check on cancer status.
- The study aims to find out who might need further treatment like HCT.
By participating, patients help researchers learn how to better treat B-ALL and potentially avoid unnecessary procedures.
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