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AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

Join a study for relapsed multiple myeloma treatment options.

Recruiting
18 years and older
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Phase 1/2

The study is testing a new treatment called AZD0120 for people with a type of blood cancer known as relapsed/refractory multiple myeloma. This is a disease where abnormal cells in the bone marrow grow uncontrollably. The treatment involves using special cells called CAR T-cells, which are modified to attack the cancer. The trial has two parts: Phase 1b to check if the treatment is safe and Phase 2 to see if it works well. To join, participants need to have tried at least three other treatments and be 18 or older. They also need to be in good general health. However, you cannot join if you have other serious health problems or if your cancer has spread to the brain.

  • The study requires participants to be adults with at least three prior treatments for multiple myeloma.
  • Participants should expect to undergo evaluations for safety and effectiveness of the treatment.
  • People with serious heart, brain, or mental health conditions cannot participate.
Study details
    Relapsed/Refractory Multiple Myeloma

NCT05850234

AstraZeneca

10 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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