This clinical trial is testing a new eye gel called **NEXAGON** (lufepirsen ophthalmic gel) for people with **PCED** (Persistent Corneal Epithelial Defects). PCED means a part of your eye's surface doesn't heal well. The study will have up to three parts: a Screening Period, an 8-week Treatment Period, and a 4-week Follow-up Period. If your eye doesn't heal or stay healed, you might get more NEXAGON for another 8 weeks. Only if your condition has not improved with regular treatments and there's no sign of infection are you eligible to join.

Key Points:

• The study lasts up to 8 weeks with a possible extension if needed.
• Participants will have multiple visits for treatment and follow-up.
• Eligibility depends on not having certain infections or eye conditions.