This study is for patients with a type of pancreatic cancer called **pancreatic ductal adenocarcinoma** that cannot be removed by surgery and has not spread to distant parts of the body. It will compare the effects of two treatments: the usual care and a new approach using higher doses of **radiation therapy**. Radiation therapy uses powerful X-rays to kill cancer cells. The new method, called **dose-escalated radiation therapy**, gives higher doses over a shorter time to see if it helps patients live longer.

The study requires patients to have already had 4-8 months of chemotherapy. Participants will be divided into two groups. One group receives the usual care (which may include more chemotherapy, standard radiation, or observation), and the other group gets the higher-dose radiation therapy. Both groups will have regular scans and tests during the study.

• This study will involve regular visits for scans and tests over several years.
• Participants may undergo different treatments based on their group assignment.
• There may be risks, such as side effects from higher-dose radiation therapy.

This study may help researchers find better ways to treat this type of cancer and potentially improve survival rates.