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A Study of Dotinurad Versus Allopurinol in Participants With Gout

Comparing Dotinurad and Allopurinol for gout treatment in a study.

Recruiting
18-75 years
All
Phase 3
This study is looking at how well a new medicine called **dotinurad** works compared to **allopurinol** for treating gout. Gout is a painful condition caused by too much uric acid in the blood, which forms tiny crystals in the joints. The study will last for 24 weeks, and it is for adults aged 18 to 75 who have had gout for at least a year and have had at least 2 flare-ups in the past year. Participants must already be taking a stable dose of allopurinol and have a uric acid level of 6.5 mg/dL or higher. **Key Points:** - The study lasts 24 weeks, with regular check-ups. - Participants must not have had kidney stones recently or be allergic to the study drugs. - There are specific requirements regarding pregnancy tests and contraceptive use for participants. To join, you must not have serious health issues that could affect your safety or the study results. The study aims to see if dotinurad can better lower uric acid levels than allopurinol.
Study details
    Gout

NCT07089875

Crystalys Therapeutics

17 October 2026

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