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Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome

Studying cranial stimulation and brain imaging for Gulf War Syndrome.

Recruiting
40-80 years
All
Phase N/A

This study aims to explore a treatment called Cranial Electrotherapy Stimulation (CES) for Gulf War Illness-related headache and pain (GWI-HAP). CES is a non-drug, non-invasive therapy using a device called Alpha-Stim™ that sends small electrical currents to the brain. It is FDA-approved for anxiety, insomnia, and pain. Researchers will use a brain scanning method called MRI, which stands for Magnetic Resonance Imaging, to understand brain changes.

Participants in this study will be veterans aged 40-80 with Gulf War Illness. They will use the CES device daily for 60 minutes over six weeks. Some will receive real CES, while others will receive a "sham" or fake version, to compare results. Pre and post-treatment assessments, including MRI scans, will be done to check for changes in the brain.

  • The study lasts 7 to 13 weeks, depending on treatment response.
  • Participants will visit Emory University for assessments and MRIs.
  • There is a chance to switch to true CES if the sham doesn't work, with extra follow-up.
Study details
    Gulf War Syndrome

NCT07151248

Emory University

17 October 2026

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