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A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

Exploring LY3537021 for chemo-related nausea in cancer patients.

Recruiting
18 years and older
All
Phase 2

This study is testing a new medicine, LY3537021, to see if it helps with nausea and vomiting caused by chemotherapy in adults with cancer. Nausea is when you feel like throwing up, and vomiting is when you actually throw up. Chemotherapy is a type of cancer treatment. People in this study will participate for about 2 months. To join, you must be starting chemotherapy for the first time, and your health should be stable (ECOG status 0-2). You can't join if you have certain health issues like brain problems (CNS metastases), uncontrolled diabetes, or heart conditions. Also, if you're pregnant or breastfeeding, you can't take part.

  • Study takes about 2 months to complete.
  • You need to be starting chemotherapy for the first time.
  • You should not have serious health issues or be pregnant.
Study details
    Nausea
    Vomiting
    Drug-Related Side Effects and Adverse Reactions
    Neoplasms

NCT07169851

Eli Lilly and Company

17 October 2026

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