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A Trial to Test Intermittent Deep Brain Stimulation of Nucleus Basalis of Meynert to Treat Alzheimers.

Testing brain stimulation for potential Alzheimer's treatment.

Recruiting
65-85 years
All
Phase 1
**A Trial to Test Intermittent Deep Brain Stimulation of Nucleus Basalis of Meynert to Treat Alzheimer's** This study is testing a new method to help people with Alzheimer's disease, which affects memory and thinking. The method is called *intermittent Deep Brain Stimulation* (DBS). DBS involves sending small electrical signals to a part of the brain called the *nucleus basalis of Meynert*. The study will have 12 participants: 6 will receive DBS and 6 will not, serving as a control group. The goal is to see if DBS can help improve or maintain thinking skills in people with Alzheimer's over two years. Information from the study may be shared, without personal details, to help with other research. **Key Points:** - **Length of Study:** The study will last at least two years. - **Participants Needed:** 12 total (6 receiving DBS and 6 as control). - **Compensation & Care:** Participants will follow regular Alzheimer's care; some will receive DBS.
Study details
    Alzheimer Dementia (AD)

NCT07218081

Augusta University

17 October 2026

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