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PF614 Analgesic Activity in Acute Postoperative Pain (PF614-301)

Join our study on pain relief after surgery with PF614.

Recruiting
18-75 years
All
Phase 3

This clinical trial is studying a drug called PF614, which is a type of pain medicine similar to oxycodone, but it releases slowly in your body over time. It is for people who will have abdominoplasty surgery, which is a surgery to remove extra skin and fat from the tummy area. The study wants to see if PF614 helps with pain better than a placebo (a pill with no medicine). Participants will take the study drug starting just before surgery and then every 12 hours for up to 4 days. They will stay at the clinic for 5 days to be watched for safety and how the drug works. After leaving, they will keep a diary about their pain and any side effects for a few more days.

  • The study lasts about 9 days in total, including staying at the clinic for 5 days.
  • Participants must take medicine and rate their pain regularly.
  • Potential side effects and rescue medication needs will be monitored closely.
Study details
    Postoperative Pain
    Acute

NCT06602271

Ensysce Biosciences

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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