This medical study is testing a drug called DISC-0974 for people who have certain blood disorders with anemia, which means they have fewer red blood cells than normal. It's a Phase 1b/2a study, meaning it's early in research and aims to see if the drug is safe and how it works.

Participants: Adults with Myelofibrosis (MF) or Myelodysplastic Syndrome (MDS), which are types of blood cancers, and have anemia. Participants must have had certain treatments stopped for at least 28 days before starting the study and meet specific health criteria.

Key points:

• The study involves taking the study drug and monitoring by doctors over time.
• Participants must stop certain medications before joining the study.
• Participants will be checked regularly to see how their bodies respond to the drug.

Before joining, participants will be screened to ensure they meet all the necessary health conditions. The study also has specific rules about who can join, such as not having certain other health problems or treatments recently. Participants are expected to follow study procedures closely.