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Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

Testing a new treatment for advanced and triple-negative breast cancer.

Recruiting
18 years and older
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Phase 1

This study is testing a new medicine called OTS167 for women with advanced breast cancer, including a tough type known as triple negative breast cancer (TNBC). The goal is to find the safest dose that can be given in a capsule form to patients. To join, women need to be 18 or older and have cancer that is not responding to standard treatments. They must be able to undergo tests and give consent to participate. Some people cannot join, like those with severe heart issues, certain infections, or if they're pregnant. The study involves taking the medicine, attending regular check-ups, and maybe having a biopsy, which is a small sample of body tissue taken for testing.

  • Duration: The study requires multiple visits to the doctor for check-ups.
  • Eligibility: Only women with certain types of advanced breast cancer can participate.
  • Risks and Safety: Participants must have no severe health issues, like heart disease, to ensure safety.
Study details
    Relapsed/Refractory Locally Advanced or Metastatic Breast Cancer and Triple Negative Breast Cancer

NCT02926690

OncoTherapy Science, Inc.

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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