**A Study for Treating Lower Limb Blockages with Indigo™ Aspiration System** This study aims to check if the Indigo™ Aspiration System is safe and works well for people with sudden lower limb blood blockages, known as *acute limb ischemia* (ALI). This condition happens when blood flow is blocked, causing pain and other problems. The Indigo™ system helps remove the blockages. **Key Points to Consider:** - **Study Length & Visits**: Participation involves regular check-ups to monitor progress. - **Eligibility & Treatment**: Participants must be 18 or older with recent blockages and will receive treatment with the Indigo™ system. - **Risks & Benefits**: As with any medical procedure, there are risks. Discuss with the doctor if this is suitable. To join, patients must meet certain criteria, like having the blockage for no more than 14 days. Some people, like those with certain medical conditions or pregnant women, cannot join. If interested, talk with your doctor to see if this study might be right for you.