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Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease

Preventive blood transfusions for pregnant women with sickle cell disease.

Recruiting
18 years and older
Female
Phase 4
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is looking at whether regular blood transfusions can help pregnant women with sickle cell disease (SCD) experience fewer health issues during their pregnancy. SCD is a genetic disorder that makes red blood cells rigid and causes pain and organ damage. For pregnant women with SCD, regular blood transfusions, which involve giving blood from a donor to replace or add to the patient's blood, might prevent problems like preeclampsia, preterm delivery, and growth issues in babies.

Participants will receive either regular blood transfusions or standard care. The study lasts about 8-10 months, covering the pregnancy and two months after delivery. Blood transfusion is the only treatment option for pregnant women with SCD since other medicines might harm the baby.

  • Participants will be in the study for about 8-10 months.
  • Participants may need regular visits for transfusions.
  • The study seeks to find better ways to care for pregnant women with SCD.
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Study details
    Sickle Cell Disease
    Pregnancy Related

NCT06979492

Emory University

17 October 2026

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