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Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma

Testing Tegavivint and Gemcitabine for tough osteosarcoma cases.

Recruiting
1-30 years
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This clinical trial studies a new treatment for osteosarcoma, a type of bone cancer that comes back or doesn't respond to usual treatments. The trial tests a combination of two drugs: Tegavivint and Gemcitabine. Tegavivint works by blocking certain signals in cancer cells, stopping them from growing. The study aims to find the best dose of these drugs and see if there are any side effects.

  • Participants will have regular visits to monitor their health and how well the treatment works.
  • The study will check how safe the drug combination is and look for any serious side effects.
  • You may need to stop taking some other medications or treatments before joining this study.
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Study details
    Osteosarcoma Recurrent
    Osteosarcoma in Children
    Relapsed Osteosarcoma
    Refractory Osteosarcoma

NCT07144254

Emory University

17 October 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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