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Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Inclisiran trial aims to prevent heart and limb issues post-intervention.

Recruiting
18 years and older
All
Phase 4
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a drug called inclisiran to see if it helps prevent heart and limb problems in patients who have had procedures like a percutaneous coronary intervention (PCI) or peripheral endovascular intervention (PVI). Inclisiran is a medicine given as a shot under the skin every six months, and it helps lower bad cholesterol (LDL-C) when used with other medicines called statins. The study will include about 6,000 patients and last around four years. Participants will either get inclisiran or a placebo (a shot with no medicine) and continue their usual care.

  • The study lasts about four years and involves regular follow-ups.
  • Participants will receive injections every six months.
  • To join, you must be over 18 and have had a PCI or PVI within 14 days.
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Study details
    Percutaneous Coronary Intervention
    Peripheral Endovascular Intervention

NCT06909565

Duke University

10 October 2026

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