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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Study comparing Soquelitinib and standard care for certain lymphomas.

Recruiting
18 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is comparing two treatments for certain types of blood cancer called peripheral T-cell lymphoma (PTCL), follicular helper T-cell lymphomas (FHTCLs), and systemic anaplastic large-cell lymphoma (sALCL). The new treatment being tested is called **soquelitinib**, which is a pill that blocks a specific protein in the body. The other treatment is the standard care, which includes medicines like belinostat or pralatrexate. About 150 people will join the study, and they will be divided into two groups—one group will get soquelitinib and the other will get standard care. The study will last for up to 2 years unless the disease worsens or side effects become too severe. If cancer progresses in those receiving standard care, they may switch over to receive soquelitinib.

  • The study lasts up to 2 years and may involve switching treatments.
  • Participants will be divided into two treatment groups: soquelitinib or standard care.
  • Participants must be 18 or older and have specific types of lymphoma.
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Study details
    Peripheral T-Cell Lymphoma
    Not Otherwise Specified
    Angioimmunoblastic T-cell Lymphoma
    Follicular T-Cell Lymphoma
    Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
    Systemic Anaplastic Large Cell Lymphoma
    Lymphoma
    T-Cell
    Peripheral
    Lymphoma
    T-Cell

NCT06561048

Corvus Pharmaceuticals, Inc.

17 October 2026

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