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A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Study on ORX750 for narcolepsy and hypersomnia patients.

Recruiting
18-65 years
All
Phase 2

Study Purpose: This study helps us learn more about the medicine ORX750 for people with sleep disorders like narcolepsy and idiopathic hypersomnia. Narcolepsy is a condition where you feel very sleepy during the day, and idiopathic hypersomnia means you feel extremely tired for no known reason. This study will check if the medicine is safe and works well over a long period.

Who Can Join: If you have narcolepsy or idiopathic hypersomnia and finished a previous study called ORX750-0201, you might be able to join. But, if you have developed other illnesses or are taking certain medicines, you might not be able to participate.

  • **Length of Study**: This is a long-term study, so it may take a while.
  • **Visits Needed**: Participants will need to be available for regular check-ups.
  • **Safety and Efficacy**: The study checks if the medicine is safe and effective over time.
Study details
    Narcolepsy Type 1
    Narcolepsy Type 2
    Idiopathic Hypersomnia

NCT07096674

Centessa Pharmaceuticals (UK) Limited

17 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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