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A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

Researching new treatments for relapsed or refractory multiple myeloma.

Recruiting
18 years and older
All
Phase 3

This study looks at how well two different treatments work for people with relapsed or refractory multiple myeloma, a type of blood cancer. Multiple myeloma happens when abnormal plasma cells build up in the bone marrow, which is the soft tissue inside bones. The study compares two treatments: JNJ-79635322 and a special type of medicine called a bispecific antibody that targets BCMA (B-cell maturation antigen) and CD3. Participants must have tried at least three other treatments before, including specific types of medicines like proteasome inhibitors and immunomodulatory drugs. They also need to have measurable disease and not be too sick from previous treatments.

  • The study requires several visits and tests to monitor health and response to the treatments.
  • Participants should not have recent major surgeries or certain infections like active hepatitis.
  • Participants may receive compensation for their time and travel expenses.
Study details
    Multiple Myeloma

NCT07258511

Janssen Research & Development, LLC

17 October 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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