This study looks at using a new medicine, relacorilant, with two existing cancer drugs, nab-paclitaxel and gemcitabine, to treat metastatic pancreatic adenocarcinoma (PDAC). PDAC is a type of cancer in the pancreas that has spread to other parts of the body. The study is in two parts. In the first part, researchers will find the best dose of relacorilant by trying different amounts on around 6 patients. In the second part, the best dose found will be given to more patients to see how well it works.
- This study requires taking medicine by mouth and receiving treatments with nab-paclitaxel and gemcitabine.
- Participants must have no previous chemotherapy for metastatic PDAC and meet specific health criteria.
- Patients should expect multiple visits and evaluations to track safety and effectiveness.