This study looks at how well a new medicine called **GB-0895** helps people aged 12-80 with severe asthma that isn't controlled by regular medicines. Asthma is a condition where the airways in your lungs become narrow, making it hard to breathe. This study involves taking either GB-0895 or a placebo (a fake treatment) through injection every 6 months. The participants will be observed over several weeks: a screening phase (5 weeks), treatment phase (52 weeks), and a follow-up phase lasting up to 142 weeks if they choose to continue in an open-label extension. **Key Points:** - The entire study can last up to 142 weeks, with visits required throughout. - Participants must have had asthma for over a year and currently use inhaled corticosteroids. - Participants cannot join if they have other major health issues or have been smokers recently. Visit www.SOLAIRIA.com for more details.