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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

Study on safety and effects of Larsucosterol for alcohol-related hepatitis.

Recruiting
18 years and older
All
Phase 3

This study is testing a drug called larsucosterol to see if it's safe and works well for people with a liver problem caused by drinking too much alcohol. This problem is called alcohol-associated hepatitis (AH). The study looks at how well people do without needing a liver transplant for three months after starting the treatment. For someone to join the study, they need to have this liver problem and meet certain health conditions. Some key tests include checking the Maddrey Discriminant Function (MDF) score and the Model for End-stage Liver Disease (MELD) score, which help doctors understand how bad the liver problem is.

  • The study lasts for 90 days, and participants need to agree to not drink alcohol and follow birth control guidelines.
  • Participants must not have certain infections or other severe health problems.
  • People in the study might be required to go to the hospital, and there are specific rules to be eligible.
Study details
    Hepatitis

NCT07428538

Bausch Health Americas, Inc.

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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