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Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

Phase 4 study: Checking long-term safety of NT-501 for MacTel Type 2.

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18 years and older
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Phase 4
This study is for people with a specific eye condition called Macular Telangiectasia Type 2 (MacTel). It looks at the long-term safety and effectiveness of a treatment called **NT-501**. NT-501 is an implant placed inside the eye. It releases a special medicine over time that might help people with MacTel. The study has three parts: - **Arm 1 and Arm 2**: These are for participants who have already received the NT-501 implant in previous studies. These parts are observational, meaning participants won't get new treatments but will be watched to see how they are doing. - **Arm 3**: This is for people who had a fake procedure (sham) in Phase 3. In this study, they can choose to get the real NT-501 implant. **Key Points to Consider**: - The study does involve long-term follow-up visits to monitor the implant's effects. - Only participants in Arm 3 will undergo a new procedure to receive the NT-501 implant. - Participants must meet certain health criteria and cannot have other eye diseases that could affect the study results.
Study details
    Macular Telangiectasia Type 2 (MacTel)

NCT06971939

Neurotech Pharmaceuticals

17 October 2026

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