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Neurophysiology of Reward Signaling in Parkinson's Disease

Exploring brain signals in Parkinson's for better understanding.

Recruiting
40 years and older
All
Phase N/A

Parkinson's Disease is a brain disorder that affects how people move. This study looks at how the brain works when people with Parkinson's take risks or seek rewards. To do this, researchers will record brain activity during deep brain stimulation (DBS) surgery. DBS is a procedure where doctors place tiny wires in the brain to help control movement. The brain recordings will focus on the corticostriatal structures, which are parts of the brain involved in decision-making.

  • Participants must be scheduled for DBS surgery at Vanderbilt University Medical Center.
  • Participants need to be at least 40 years old and able to understand and follow instructions during surgery.
  • Participation involves being part of the study during surgery, but there are no extra visits required.

This study helps researchers understand the non-movement symptoms of Parkinson's, which are often overlooked but very important. There is no mention of compensation for participating, and the main risk relates to the surgical procedure itself. If you're eligible and interested, consult your doctor to see if this study is right for you.

Study details
    Parkinson Disease

NCT07409207

Vanderbilt University Medical Center

17 April 2026

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