This study tests a new method called PET (Positron Emission Tomography) to see if it can safely and accurately detect a protein called α-synuclein in the brain. This protein is involved in diseases like Parkinson's Disease. The new PET tracer used is named [18F]ACI-15916.
- The study may last up to 10 weeks, or 14 weeks for some parts.
- Participants may have to visit the clinic multiple times for tests and scans.
- After the PET scan, participants will be contacted by phone to discuss any side effects.
People with and without these conditions can join. Some participants may have a second PET scan to check the results are consistent. Healthy people will also have a whole-body scan to measure radiation exposure. To join, participants need to be generally healthy, have a normal weight, and be able to follow study procedures. Pregnant women and people with certain health conditions cannot participate.
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