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Globus Pallidus Stimulation to Treat Insomnia

Clinical trial exploring brain stimulation to help with insomnia.

Recruiting
40-80 years
All
Phase N/A

Study Overview: This study is exploring if a specific type of deep brain stimulation (DBS) can help people with insomnia. DBS is a treatment where small electrical pulses are sent to a part of the brain to help it work better. In this case, the focus is on the globus pallidus externa (GPe), a region in the brain. Insomnia means having trouble sleeping. This study is specifically for people with a movement disorder called Parkinsonism.

Eligibility: To join, you should be between 40-80 years old and have had Parkinsonism for 7-20 years with severe insomnia. There are some reasons you might not be able to join, such as having dementia, other serious brain diseases, or sleep problems like severe sleep apnea. If you’ve had certain brain surgeries before or use sleep medicines, you might not qualify.

  • Study Duration and Visits: You need to travel to Jacksonville for follow-up visits after the procedure.
  • Risks: There are risks with brain stimulation and some conditions may prevent participation.
  • Treatment: DBS involves a surgical procedure to place electrodes in the brain.
Study details
    Parkinson Disease

NCT04116996

Mayo Clinic

17 April 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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