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A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease

Study on SUL-238's effects in early, untreated Parkinson's patients.

Recruiting
40 years and older
All
Phase 2
This clinical study is testing a new drug called **SUL-238** for people with early, untreated Parkinson's Disease (PD). The study uses a special scan called **MRS** (like an MRI) to see how the drug affects brain chemicals related to energy called phosphates. The drug is compared to a **placebo**, which looks like the drug but has no active ingredients. The study will last for about 12 weeks, including a 4-week treatment period. During this time, participants will take SUL-238 or the placebo daily and visit the clinic every two weeks for checkups. Participants will also need to keep a diary about their symptoms and any side effects. **Key Points:** - Duration: Approximately 12 weeks, with 4 weeks of daily treatment. - Clinic Visits: Every two weeks during treatment and a final visit 28 days after the last dose. - Participants must fast (no eating) before some doses and tests. This study checks if SUL-238 improves brain energy and what side effects might occur. Participants must be at least 40 years old, recently diagnosed with PD, and willing to follow study rules.
Study details
    Parkinson's Disease (PD)

NCT07322887

GEN İlaç ve Sağlık Ürünleri A.Ş.

22 August 2026

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