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Evaluating the Effect of Mirtazapine on Anxiety in Parkinson's Disease Patients

Testing if Mirtazapine helps reduce anxiety in Parkinson's patients.

Recruiting
18 years and older
All
Phase 2

This study looks at how *mirtazapine*, a medication, affects anxiety in people with Parkinson's Disease (PD). The study lasts for 12 weeks and takes place at a hospital's Movement Disorders Clinic. It is a double-blind study, meaning neither the patients nor the researchers know who is getting the actual medication or a placebo (a pill with no medicine). Mirtazapine is given in a dose of 15 mg once a day. The study checks for anxiety, depression, fatigue, sleep issues, and quality of life at the start, 4 weeks, and 12 weeks into the study.

  • The study lasts 12 weeks and involves several visits to the clinic.
  • Participants must be over 17 years old with mild/moderate Parkinson's Disease.
  • People with certain medical histories like major depression, cardiovascular disease, or recent use of certain medications cannot join.
Study details
    Parkinson Disease
    Anxiety

NCT06530290

Leila Dargahi. PharmD PhD

17 April 2026

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