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Electrophysiology-based DBS Programming for PD

Exploring new DBS programming for Parkinson's in a clinical trial.

Recruiting
21-89 years
All
Phase N/A

Deep brain stimulation (DBS) helps reduce movement problems in Parkinson's disease (PD). This study aims to make DBS programming faster by using local field potentials (LFPs), which are tiny electrical signals in the brain, to find the best settings. The study compares this new method to the traditional way doctors set up DBS.

Up to 30 people with DBS devices will join. Their devices can both give therapy and record brain activity. Doctors will try three different ways to set up the DBS: the usual doctor method, based on LFPs, and a mix of both. The first and third ways follow current medical rules, while the second uses a new science-based method. This new method might end up with the same settings as the usual methods, so it's safe.

  • Participants need to be 21-89 years old with Parkinson's and have a Medtronic DBS device.
  • Participants must agree to join the study during their first programming session.
  • The study will include up to four different DBS setting trials.
Study details
    Parkinson's Disease (PD)

NCT07348705

University of Florida

17 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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