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A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LBT-3627 in Healthy Participants and in Participants With Parkinson's Disease.

Study on safety and effects of LBT-3627 for Parkinson's patients.

Recruiting
30-89 years
All
Phase 1

This study is looking at the safety of a new drug called LBT-3627. It includes two parts: one with a single dose and one with multiple doses. It will involve healthy people and those with Parkinson's Disease, a disorder affecting movement.

Phase Ia starts with healthy volunteers, then moves to Parkinson’s patients. Phase Ib involves only Parkinson's patients with multiple doses. They will test how the body handles the drug and its effects.

To take part, you need to be between 30-89 years old, have a healthy body weight, and normal heart and safety tests. Women must not be able to have children or use strong birth control. You can't have had recent vaccines, certain medicines, or serious illnesses.

  • The study includes different groups with increasing doses.
  • Participants must meet specific health criteria.
  • The study involves both single and multiple dose phases.

There's a focus on safety throughout. If you have Parkinson's, you need a diagnosis from a doctor. You'll need to manage your current medication carefully during the study.

Study details
    Parkinson Disease

NCT06466525

Longevity Biotech Australia Pty Ltd (subsidiary)

29 August 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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