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Retinal Imaging in Neurodegenerative Disease

Studying eye images to understand brain degenerative diseases.

Recruiting
18 years and older
All
Phase N/A
**Retinal Imaging in Neurodegenerative Disease Study** This study is exploring how changes in the eyes might relate to brain diseases like Alzheimer's and Parkinson’s. It uses special cameras and scans: *OCT* (Optical Coherence Tomography) and *OCTA* (OCT Angiography) to take pictures of the tiny blood vessels and structures in the eyes. These tools help researchers find early signs of disease by looking at the eyes' blood flow and structure. The study hopes to show that these eye scans can be a useful tool in detecting brain diseases early. **Key Points:** - **Participation Duration:** You will need to visit the study site for eye scans. - **Eligibility:** Adults with or without brain diseases can join, but you shouldn't have had eye surgeries except for cataracts. - **Benefits:** Help improve early detection of brain diseases, though there may be no direct benefit to you. *This study is a chance to contribute to important research that could help with early diagnosis of brain diseases.*
Study details
    Alzheimer's Disease
    Mild Cognitive Impairment
    Parkinson's Disease
    Multiple Sclerosis
    Huntington Disease
    Lewy Body Dementia
    Frontotemporal Dementia
    Amyotrophic Lateral Sclerosis (ALS)
    APOE-4 Positive
    Traumatic Brain Injury
    Concussion
    Post-Traumatic Stress Disorder
    Down Syndrome
    Neuro-Degenerative Disease
    Normal Cognition

NCT03233646

Duke University

17 April 2026

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