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Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease

Exploring swallowing challenges in Parkinson's and how the brain adapts.

Recruiting
18 years and older
All
Phase N/A

Parkinson's disease (PD) is a brain disorder and can cause swallowing problems called dysphagia. This can lead to serious issues like pneumonia or not getting enough nutrients. This study will look at 100 PD patients to understand why dysphagia happens and how the brain might try to fix it. Researchers will use a test called FEES to check swallowing, and also collect blood samples to find markers of inflammation and neurodegeneration. They will use functional magnetic resonance imaging (fMRI) to see brain activity during swallowing. This will help find ways to improve treatments and make life better for PD patients.

  • Study Length: Involves various tests and assessments.
  • Visits Needed: Includes clinical and imaging visits.
  • Risks: Mainly related to standard medical tests.
Study details
    Parkinsons Disease (PD)
    Oropharyngeal Dysphagia

NCT07299448

Heinrich-Heine University, Duesseldorf

17 April 2026

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