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Personalized rTMS Protocol Based on Functional Reserve to Enhance Ambulatory Function in PD Patients

Personalized brain therapy to help improve walking in Parkinson's patients.

Recruiting
50 years and older
All
Phase N/A

This study explores how a treatment called repetitive transcranial magnetic stimulation (rTMS) can help people with Parkinson's disease, a brain disorder affecting movement. The usual method of rTMS is to stimulate the part of the brain called the primary motor cortex (M1) to help with movement and walking. However, this study wants to see if customizing the rTMS treatment based on each person's functional reserve (how well their brain can recover and function) could work better than using the same treatment for everyone.

Participants will be divided into two groups based on their Timed Up and Go Test (TUG) results: those with stronger movement abilities and those with stronger thinking abilities. Each group will receive rTMS treatment to see which method works best.

  • The study is for people 50 years and older with Parkinson's who can walk without help.
  • Participants will be randomly assigned to receive different rTMS treatments.
  • This study is not suitable for those with additional neurological or psychiatric conditions.
Study details
    Parkinson's Disease and Parkinsonism

NCT06350617

Samsung Medical Center

17 April 2026

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