Image

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

Boosting exercise may help slow cognitive decline in certain brain disorders.

Recruiting
50-80 years
All
Phase N/A

This study focuses on people with **iRBD** (Isolated REM Sleep Behavior Disorder), which often leads to Parkinson's disease or dementia with Lewy bodies. It aims to see if being more active can help slow down brain problems in people with iRBD. An app on your smartphone will help you be more active for one year. The study is "randomized" (participants are randomly chosen for different groups) and "double-blind" (neither the participants nor the researchers know who is in which group) to ensure fairness. The main thing being checked is changes in brain function using tests and MRI scans.

Key Points:

  • The study lasts for one year and uses a smartphone app to boost physical activity.
  • Participants must be aged 50-80, have basic smartphone skills, and speak German well.
  • Excludes people with major heart issues or cognitive issues that make smartphone use hard.

If you're interested and meet the criteria, this study might help improve understanding of how exercise affects brain health in early stages of certain neurodegenerative diseases.

Study details
    Parkinson Disease
    Prodromal Stage
    Neurodegenerative Diseases
    Basal Ganglia Diseases
    Central Nervous System Diseases
    Synucleinopathies
    Nervous System Diseases
    Cerebral Disorder
    Brain Diseases
    Parkinsonian Disorders

NCT07324330

University Hospital, Bonn

17 April 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.