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Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease

Testing brain stimulation for memory issues in Parkinson's patients.

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Phase N/A

This study looks at two types of non-invasive brain stimulation to help people with mild memory and thinking problems related to Parkinson's disease. One method is called rTMS, or repetitive transcranial magnetic stimulation, which uses magnets to stimulate the brain. The other is tDCS, or transcranial direct current stimulation, which uses a small electric current. Both methods target a brain area linked to thinking skills. Researchers want to see if people like these treatments and if they are easy to use. Participants will go through four phases over 16 weeks, including two treatment phases. MRI scans will help personalize the treatment.

  • Duration: 16 weeks, with 4 phases (each 4 weeks long).
  • Visits: rTMS requires travel to a clinic; tDCS can be done at home.
  • Eligibility: Must have mild cognitive impairment with Parkinson's, and meet specific health criteria.
Study details
    Parkinson Disease
    Mild Cognitive Impairment

NCT06399731

Amsterdam UMC

17 April 2026

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