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The CurePSP Genetics Program

Join the CurePSP Genetics Program to help advance research.

Recruiting
35 years and older
All
Phase N/A

This study is looking to understand more about certain neurological conditions by studying DNA. PSP stands for Progressive Supranuclear Palsy, CBS is Corticobasal Syndrome, and MSA is Multiple System Atrophy. These are brain disorders that affect movement and other functions. Researchers will collect blood samples from up to 1,000 adults with these conditions to study their genetics. They will use a special technique called whole genome sequencing to look at DNA, but this is not the same as medical testing you get at your doctor’s office. The study is safe with very low risk. This research might help us understand these diseases better and could lead to new treatments in the future.

  • The study will not change your current medical treatment.
  • It involves only a blood sample and surveys.
  • Participants can learn about their genetic results if they choose to.

To join, you must be 35 or older and have or be related to someone with these conditions. People with recent blood transfusions or some blood cancers cannot participate.

Study details
    PSP
    PSP - Progressive Supranuclear Palsy
    Corticobasal Syndrome
    Corticobasal Syndrome(CBS)
    Corticobasal Degeneration Syndrome
    Corticobasal Degeneration
    Corticobasal Degeneration (CBD)
    Corticobasal Syndrome (CBS)
    MSA
    MSA - Multiple System Atrophy
    MSA-C
    Multiple System Atrophy
    Multiple System Atrophy (MSA) With Orthostatic Hypotension
    Multiple System Atrophy - Cerebellar Subtype (MSA-C)
    Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
    Multiple System Atrophy
    Cerebellar Type
    Multiple System Atrophy
    Parkinsonian Type
    Progressive Supranuclear Palsy
    Progressive Supranuclear Palsy(PSP)
    Progressive Supranuclear Palsy (PSP)

NCT06647641

Massachusetts General Hospital

17 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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