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Understanding Motivation in Parkinson's Patients Through Neurophysiology

Studying Parkinson's motivation through brain activity research.

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is about understanding how motivation works in people with Parkinson's Disease (PD) by using a special device called the Medtronic Percept DBS. DBS, or Deep Brain Stimulation, is a treatment that uses electric signals to help control symptoms of PD. The study combines tasks and recordings from the brain to see how DBS affects motivation, especially related to effort, reward, and timing.

Participants will do tasks that show how they make decisions when working for rewards. These tasks happen both at home and in clinics. They will keep taking their regular medicines and will try tasks with DBS turned on and off. The special Percept device records brain activity and sends data from home. Participants will also wear a gadget that tracks movement, sleep, and heart rate.

By looking at changes in how fast and well participants do tasks, the study hopes to learn more about symptoms that aren't related to movement. This can help make DBS treatments better in the future.

  • Study involves home and clinic visits.
  • Participants need a Medtronic Percept DBS device.
  • Excludes those under 18 or with severe cognitive issues.
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Study details
    Parkinson Disease
    Deep Brain Stimulation
    Motivation

NCT05065151

University of California, San Francisco

17 April 2026

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