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[18F]F-DOPA Imaging in Patients With Autonomic Failure

Participate in a study using [18F]F-DOPA imaging for autonomic failure.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

Study Overview: This research focuses on understanding a group of diseases called alpha-synucleinopathies. These diseases, like Parkinson's Disease (PD), Multiple System Atrophy (MSA), and Dementia with Lewy Bodies (DLB), are linked to nerve problems due to a protein build-up in the brain. The study uses a special imaging technique called [18F]F-DOPA PET, which helps doctors see changes in dopamine, a brain chemical, to predict disease changes in patients with Pure Autonomic Failure (PAF).

  • Length and Visits: Participants need to attend multiple visits for imaging. The duration of each visit varies.
  • Eligibility: Open to adults 18 and older with PAF, possible PD, MSA, or DLB, and healthy adults. Certain medical conditions or devices may exclude you.
  • Risks: Pregnant women and those with certain implants are excluded due to potential risks.
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Study details
    Autonomic Failure
    Pure Autonomic Failure
    Parkinson Disease
    Multiple System Atrophy
    Dementia With Lewy Bodies

NCT04246437

Daniel Claassen

17 April 2026

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