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Effects of Propofol on Brain Function in Patients With Parkinson's Disease

Studying how Propofol affects brain function in Parkinson's patients.

Recruiting
18-80 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

Study Overview: This study explores how the drug propofol affects the brain in patients with Parkinson's Disease (PD). Propofol is an anesthetic that helps patients sleep during surgeries. It works quickly and has effects like reducing anxiety and relaxing muscles. In PD, natural antioxidants are low, and propofol might protect the brain by reducing oxidative stress (damage caused by harmful molecules). The study will compare how much propofol is needed for PD patients versus non-PD patients during surgery and observe changes in brain activity.

  • This study involves comparing PD patients undergoing DBS (Deep Brain Stimulation) surgery with non-PD patients having other surgeries.
  • Participants must be aged 18-80, and free from certain conditions like sleep apnea or severe organ issues.
  • Participants will be monitored for changes in brain function during surgeries.
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Study details
    PD - Parkinson's Disease

NCT05895019

Beijing Tiantan Hospital

17 April 2026

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