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Imaging Biomarkers of FOG Response to DBS

Study on brain scans to see DBS effects on freezing of gait.

Recruiting
40 years and older
All
Phase 4

**Study:** This study focuses on people with Parkinson's Disease (PD) who have trouble walking, also known as Freezing of Gait (FOG). It involves a treatment called Deep Brain Stimulation (DBS), which uses a device to send electrical signals to the brain.

**Process:** Before the DBS procedure, participants will have a brain scan called an MRI and tests that check their walking and thinking skills. After DBS, these tests will be repeated several times over a year to see how well the treatment is working. Participants will visit the study site seven times in total.

**Key Points:**

  • **Length:** Study lasts about one year with seven visits.
  • **Assessments:** Includes MRI scans and tests for walking and cognitive skills.
  • **Eligibility:** Must be over 40, have PD and FOG, and be a candidate for DBS surgery.

**Note:** Participants should not have other walking issues not related to PD or any metal in their body that can't go into an MRI machine.

Study details
    Freezing of Gait Symptoms in Parkinson's Disease
    Deep Brain Stimulation

NCT06951906

Medical University of South Carolina

15 August 2026

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