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Theta Deep Brain Stimulation for Cognitive Enhancement in Parkinson's Disease

Join our study on deep brain stimulation for Parkinson's cognitive health.

Recruiting
18-80 years
All
Phase N/A

Parkinson's Disease (PD) can cause problems with thinking, called cognitive impairment. Over time, many people with PD may face dementia, which is severe memory and thinking trouble. This study looks at using a treatment called *Theta Deep Brain Stimulation* (DBS) to help improve thinking skills in PD. The subthalamic nucleus (STN) is a part of the brain involved in controlling movement and behavior. Researchers believe stimulating this area at a specific frequency, called theta (4-8 Hz), can help with thinking in PD patients. The study will be conducted with patients who have already had DBS surgery and meet certain criteria.

  • Study Length and Visits: Participants will attend the Vancouver General Hospital DBS clinic multiple times.
  • Eligibility: Participants must have had DBS surgery with specific imaging and be three months post-surgery.
  • Risks: Participants might feel unwanted effects from the stimulation, and adjustments will be made if needed.
Study details
    Parkinson Disease
    Cognitive Impairment

NCT06518824

University of British Columbia

17 April 2026

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