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Evaluation of the Efficacy and Safety of Fecal Microbiota Transplantation for Constipation in Parkinson's Disease

Testing if fecal transplants help constipation in Parkinson's patients.

Recruiting
40-75 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is checking if taking Fecal Microbiota Transplantation (FMT) capsules can help with constipation in people with Parkinson's Disease (PD). Constipation means having trouble with bowel movements. In the study, participants will get either FMT capsules or placebo capsules. Placebo capsules look and smell the same but only have milk powder inside.

Participants will take 6 FMT capsules twice a week for 24 weeks. During this time, they will visit the doctor to see if their constipation and quality of life improve. Doctors will also collect poop samples for some special tests and check blood for a medicine called levodopa that helps with Parkinson’s.

  • Participation lasts for 24 weeks with regular doctor visits.
  • Participants may receive FMT or placebo capsules.
  • Fecal and blood samples will be collected for testing.
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Study details
    Parkinson Disease

NCT06388863

Shanghai Zhongshan Hospital

17 April 2026

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