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Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients

Studying brain stimulation effects on tremors and walking in Parkinson's patients.

Recruiting
50 years and older
All
Phase N/A

This study is testing a new treatment called **targeted temporal interference stimulation (TIS)** to help people with Parkinson's disease. Parkinson’s disease is a brain disorder that causes shaking (tremors) and trouble walking (gait disturbance). The cerebellum, a part of the brain, helps control movement and balance. Scientists think using TIS on the cerebellum could improve these symptoms.

In this study, participants will receive either the real TIS treatment or a fake one (sham) without knowing which they get. Doctors will measure changes using the **Unified Parkinson Disease Rating Scale (UPDRS)**, a gait test, and a tremor test.

  • The study is for people 50 years or older with Parkinson's disease.
  • Participants will need to visit the clinic for tests before and after the treatment.
  • The study requires a stable medication dosage for at least 4 weeks before joining.

If you have certain mental health conditions, metal implants, or other health issues, you may not be eligible. This study could offer a new way to help manage Parkinson's symptoms.

Study details
    Parkinson's Disease
    Movement Disorders

NCT07384442

YangPan

17 April 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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