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Characterizing the Pathophysiological Role of the Pallido-thalamocortical Motor Pathway in Parkinson's Disease.

Studying brain pathways in Parkinson's disease.

Recruiting
21-75 years
All
Phase N/A

Parkinson's Disease Study: This study is looking at how parts of the brain talk to each other in people with Parkinson's disease. Parkinson's disease affects movement, and the study wants to see if we can find the best spot in the brain to help with movement using a treatment called Deep Brain Stimulation (DBS). DBS is a surgery where a doctor places a small device, called a lead, in the brain to help control movement. For this study, we'll also use an ECoG strip, a thin film with sensors that record brain activity during the surgery. The ECoG strip will be put through the same hole as the DBS lead, so no extra holes are needed. We'll take quick X-ray pictures to make sure everything is in the right place, but this means people who have had a lot of X-rays recently might not join.

  • The study involves brain surgery and some radiation exposure.
  • Participants will perform tasks to see how the brain works during movement.
  • Only people aged 21-75 with planned DBS surgery and no recent high radiation exposure can join.
Study details
    Parkinson Disease

NCT06692920

University of Minnesota

17 April 2026

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