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Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

Studying movement sensors to understand blood pressure symptoms when standing.

Recruiting
40-80 years
All
Phase N/A

This study checks if an activity monitor can help track symptoms in patients with neurogenic orthostatic hypotension (nOH). nOH is when your blood pressure drops when standing, making you feel dizzy or lightheaded. Patients will wear an activity monitor for two weeks. One week, they'll take a placebo (a harmless pill with no medicine), and the other week, their usual medicine. The monitor measures how long they stay upright (standing or walking). Researchers will compare this data to see if the monitor shows improvements better than questionnaires.

  • Study Length: 2 weeks of monitoring, with a 1-week break in between.
  • Location: Conducted at home with caregiver help.
  • Participation: Must be aged 40-80 and on specific treatments for nOH.
Study details
    Orthostatic; Hypotension
    Neurogenic
    Autonomic Failure
    Pure Autonomic Failure
    Multiple System Atrophy
    Orthostatic; Hypotension
    Parkinsonism

NCT04782830

Vanderbilt University Medical Center

17 April 2026

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