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Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease

Exploring Lemborexant's impact on sleep and movement in Parkinson's.

Recruiting
50 years and older
All
Phase 4

This study looks at how a drug called Lemborexant might help people with Parkinson's disease who have trouble moving and sleeping. Parkinson's is a disease that affects movement, causing slow movements, shaking, and stiffness. Many people with Parkinson's also have trouble sleeping, which can make things worse.

Lemborexant is a type of medicine that blocks something in the brain called orexin, which helps with sleep and movement. The study will see if taking Lemborexant can help with these problems. People in the study will take 5 mg of Lemborexant or a placebo (a fake pill) each night for 28 days. They will visit the study team four times during this period to check on their progress.

  • Study Length: 28 days with 4 visits.
  • Eligibility: Must be 50 or older with Parkinson's and sleep problems.
  • Compensation: Participants will receive benefits for taking part.
Study details
    Parkinson's Disease
    Insomnia
    Motor Disorder

NCT07384429

YangPan

17 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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