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Personalized Real-Time DBS and PD Mechanisms

Study on DBS for Parkinson's, but no guaranteed treatments.

Recruiting
18-80 years
All
Phase 4

This study focuses on patients with Parkinson's disease (PD) having surgery for deep brain stimulation (DBS), a treatment involving electrical signals to the brain to help manage symptoms. Researchers aim to understand how the brain's beta band oscillations (rhythmic brain activity) affect PD symptoms like bradykinesia (slowness of movement) and rigidity (stiffness). They'll use closed-loop DBS, a method that adjusts in real time based on brain activity, combined with levodopa (a common PD medication) to study these effects. The findings could improve personalized DBS for PD.

  • Participants must be eligible for DBS surgery and able to delay daily medication.
  • Participation involves brain activity recording and adjustments during surgery.
  • Risks include surgery-related complications and potential medication delays.
Study details
    Parkinson Disease

NCT06013956

David Escobar

29 August 2026

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