Study Overview: This study aims to see how a probiotic called Clostridium Butyricum Miyairisan helps with both movement and non-movement symptoms in people with Parkinson's disease. Parkinson's disease is a condition that affects how the body moves and can cause tremors (shaking) and stiffness.

Study Details: The study is conducted at one location and will not randomly assign participants to different groups. Participants will be divided into experimental and observation groups. The study will involve taking the probiotic at specific times, evaluating symptoms with scales, and collecting samples. The doctor will explain everything and get your written permission before you start.

Eligibility: If you are a man or woman over 20 years old and have been diagnosed with Parkinson's disease, you may qualify. However, if you have Parkinson's disease Dementia or are lactose intolerant, you cannot participate.

• Participation involves taking a probiotic and having regular evaluations.
• The study is not randomized; participants are knowingly assigned to groups.
• Written consent is required; the doctor will guide you through the process.