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A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

Join a study on new treatment for challenging Parkinson's tremors.

Recruiting
30-99 years
All
Phase N/A

This study looks at the long-term safety and effectiveness of a procedure called thalamotomy for people with Tremor Dominant Parkinson's Disease (TDPD). Thalamotomy is a surgery that helps reduce tremors, which are shaky movements. The study uses a machine called Exablate Neuro to perform this surgery. Participants have already had this procedure done on one side of their brain.

Researchers will check in with participants at different times: right after the surgery, and then at 1, 3, 6, and 12 months, and then once a year for five years. They'll look at Adverse Events (AEs), which are any side effects or problems, and also how much medication you need, and how well the treatment works using special tests like Clinical Rating Scale for Tremor (CRST) and Unified Parkinson's Disease Rating Scale.

  • Participation lasts up to 5 years with regular check-ups.
  • Participants need to be 30 years or older.
  • You must be willing to follow all study rules and attend all visits.
Study details
    Tremor Associated With Tremor Dominant Parkinson's Disease

NCT04991831

InSightec

17 April 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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